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arXiv — cs.AI preprintsInternational19 October 2026

Beyond Uncertainty Reduction: Calibrated Planning for Interactive Diagnosis

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arXiv:2608.27847v2 Announce Type: replace Abstract: Interactive medical diagnosis requires an agent to gather patient evidence through sequential questions before committing to a diagnosis. Large language models (LLMs) now make such consultations feasible, and existing approaches typically select questions by how much they reduce uncertainty among candidate diseases. However, this objective is insensitive to the unequal clinical costs of diagnostic errors and omitted severe alternatives, so minimizing uncertainty need not minimize final diagnostic loss. To bridge this gap, we propose CaRDI (Ca
— arXiv — cs.AI preprints

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