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arXiv — cs.AI preprintsInternational16 October 2026

AI Consilium: a Benchmark of LLM Clinical Multidisciplinary Second Opinions

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arXiv:2610.22298v1 Announce Type: cross Abstract: Large language models (LLMs) can generate differential diagnoses for complex cases, but a useful second opinion must also be factually grounded, clinically coherent, actionable, and safe. We developed a multidimensional benchmark using 300 diagnostically resolved NEJM--MedQA cases: 110 for physician reference ratings and Judge calibration and 190 for held-out evaluation. Eight single-model pipelines generated independent role-specific opinions and interactive-consilium reports under free-form and structured clinical-reasoning conditions. A phys
— arXiv — cs.AI preprints

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