Knee3DVLM: Dual-Sequence Full-Volume Vision-Language Modeling for Comprehensive Knee MRI Assessment

arXiv:2610.08482v1 Announce Type: cross Abstract: Vision-language models (VLMs) are increasingly being applied to three-dimensional medical imaging, but their application to knee MRI remains limited, particularly for interpreting the complementary sequences used in clinical practice. We introduce Knee3DVLM, a sequence-aware VLM that uses full-volume DESS and fluid-sensitive TSE MRI to predict 57 anatomically resolved binary diagnostic targets derived from the MRI Osteoarthritis Knee Score (MOAKS) for structured reporting. We evaluated DESS-only, TSE-only, and paired DESS-TSE configurations usi

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